This week we’re featuring Dr Holly Shiels – a senior lecturer in cardiac physiology. Without any further introduction, let’s get right into it.
Please explain your research for the general public in around 10 sentences or less
Survival of nearly all vertebrate animals depends on maintained cardiac function. Environmental changes, such as temperature and oxygen fluctuations, can dramatically affect the ability of the heart to maintain normal function. To this end, we explore strategies of cardiac adaptation that permit maintenance of heart function in ectotherms living in fluctuating environments. We try to understand this across levels of biological organisation and in a range of species including tuna, trout, turtle, caiman, zebrafish, catfish, varanid lizard, rat and hamster and even human!
What benefit does your research give to the people reading this blog?
Recently we have been working on the effect of oil spill pollutants on the hearts of fish. This is important for understanding the implications of environmental disasters on aquatic species. Fish have a number of uses for humans – from food, sport and hobbies to thriving ecosystems which help sustain the environment here on Earth.
How did you first become interested in your research area?
During my PhD I had my first chance to work on large pelagic fish like tuna and swordfish. These animals move through thermoclines and hypoxic zones in the ocean and their heart beats throughout. I found this fascinating and am still trying to understand how they do it today!
Did you have any science heroes growing up? Who inspired you to do science?
Growing up in Canada there was a TV program called ‘The Nature of Things’ it was hosted by an Environmental Science Professor at the University of British Columbia called David Suzuki. I liked it because it presented nature and the impact humans were having on it. This was a novel approach for nature documentaries in the 70s and it made me think that I had a responsibility to understand mechanisms of environmental adaption.
How has working here in Manchester helped you?
Manchester is a large institution with excellent facilities that attract world class scientists in nearly every discipline. This is a great benefit as it means the questions I can ask in my research are nearly endless; there will always be the equipment and know-how to address interesting questions.
What do you do outside of work?
I enjoy time with my family and friends.