Almost £1.3 million has been awarded from Arthritis Research UK to scientists at the University of Manchester.
Faculty scientist Dr Qing-Jun Meng and his colleague, Dr Julie Gibbs from the Faculty of Medical and Human Sciences, have been awarded the fellowships (worth £845,918 and £434,767 respectively) in order to study the effects the body clock has on two common types of arthritis: osteoarthritis and rheumatoid arthritis. It is well known that the symptoms of arthritis fluctuate during the day and it is thought that this is linked to our internal body clocks.
Dr Meng is an expert in cartilage and joint damage linked to the 24 hour body clock of the human body. He’s now looking to use the fellowship to get a better understanding of how disruptions in the natural body clock could lead to an increased risk of developing osteoarthritis. He says:
“I am very pleased to receive this fantastic award, which will enable me to continue in this potentially very fruitful area of biomedical research. I believe this research will provide novel and medically relevant insights into one of the most common joint diseases that affect most elderly.”
Dr Gibbs’ research specialises in body clocks and inflammation. In particular, her research has shown that the body clock is a key regulator in inflammation. Arthritis is an inflammatory disease of the joints and so a better understanding of how the body clock helps to control inflammation may give us a greater insight into the role body clocks play in arthritis.
The duo are part of a larger team based here at The University of Manchester which collectively makes up one of the largest and most productive clock research communities in the world. Having successfully collaborated on previous projects, both researchers are looking to use their complementary research skills to tackle one of the biggest research problems in the arthritis field.
Professor Ian Roberts, Associate Dean for Research of the University’s Faculty of Life Sciences, said: “We are delighted by the two recent prestigious fellowship awards to these two excellent young researchers. They reflect the quality of research on body clocks ongoing in both faculties and offer a real opportunity to answer important questions on body clocks and human disease.”
Dr Stephen Simpson, Director of Research and Programmes at Arthritis Research UK commented: “…we’re hopeful that these two fellowships will take us closer to much-needed, more effective treatments for people with these painful, debilitating conditions.”