On the back of Gloria’s glowing recommendation, we decided to track down David Brough who is a research fellow within the Faculty. In this episode you’ll get to find out about David’s research into inflammation and how Manchester has helped him as a young researcher.


Could you please explain your research, for the layman, in ten sentences or less?

David Brough holding the Love Life Sciences board.So I work on a process called inflammation which is our body’s response to danger. Unfortunately, sometimes during disease this inflammatory response makes the disease worse. I try to understand these processes to see if we can identify new ways to treat disease.

How does this research benefit the person reading the blog?

So my research is really basic and is at a fundamental level, but hopefully discoveries that I make will, in the future, translate to human benefit. The research I do, for the people reading this blog, will hopefully, in 10, 15, 20 years’ time will have informed some of the treatments or practices to treat inflammatory disease. Inflammatory disease encompasses very common, mainstream disease: Cardiovascular disease, inflammatory skin diseases such as ‎Psoriasis or brain diseases such as stroke or Alzheimer’s disease.

How did you first get interested in inflammation?

I was always very interested in science and biology and I was always interested in basic mechanisms in biology which could contribute to disease. It was during my PhD that I became interested in inflammation. Inflammation is a great area to work in – particularly the processes I work on because there’s so much biology we don’t understand and it is directly relevant to people of all ages because it’s a major contributor to disease processes. It’s easy to understand and justify the reasons for studying these inflammatory processes.

Do you have any science heroes? Who inspired you?

I was always very interested in stories of scientific discovery such as the discovery of DNA and Penicillin. My scientific heroes have always been scientists who have made great breakthroughs. However, there hasn’t really been any one particular person who I inspired to be.

How has working in Manchester helped you?
As a young researcher, Manchester has been a supportive environment and I have great colleagues in my department. They are people who have complimentary research interests and I have been able to work effectively and collaborate well. There have been a lot of opportunities to develop my career.

What do you do outside of work?

When I’m not working here, I have two children who keep me very busy. I do various sports – I’m involved in martial arts and I am a jujitsu instructor, which I do several times a week.


Thank you David for sharing a bit more about your research and your role in the Faculty! Come back next week for another exciting look at some of the people who are involved with the Faculty of Life Sciences.

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