fruitfly (1)Faculty scientists have been awarded £2.8million to further understanding of how cells develop and form particular types of body tissue. The award is part of a £17.7million cash injection from the Biotechnology and Biological Sciences Research Council (BBSRC) which aims to harness the power of bioscience to make significant impacts in healthcare and agriculture. The Manchester team will collaborate with the University of Cambridge and University College London.

Using fruit flies as a model system, researchers will answer important questions regarding how much of each gene product is expressed at one time, which version of each gene is expressed, and which protein partners interact with the gene. Faculty scientist Professor Simon Hubbard explained:

“This could help explain how gene defects lead to abnormal development. Our simonhubbarddevelopment is governed by the complex interplay between the proteins encoded by our genes. Careful control of these proteins at a specific time during development dictates the fate of cells and the tissues they will form. While some of this information is contained within the genome sequence, we currently lack the full picture of what happens during development in the embryo. This project will close the gap in knowledge using both experimental and computational science. ”

The research is funded through the BBSRC’s Strategic Longer and Larger Awards (sLoLas,) which give world-leading research teams the time and resources they require. Professor Jackie Hunter, BBSRC’s Chief Executive, said:

“This public funding offers long-term support to address major research challenges, while building research capacity in important areas and maximising economic and social benefits for the UK.”

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